Lorazepam (Ativan) 2.5 mg

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Lorazepam (Ativan) 2.5 mg


Temesta® 2.5mg Tablets/Lorazepam 2.5mg Tablets
Your medicine is known by the above names, but will be referred to as Lorazepam Tablets throughout this:
Patient Information Leaflet
Read all of this leaflet carefully before you start taking this medicine.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you. Do not pass it on to others.
It may harm them, even if their symptoms are the same as yours.
• If any of the side-effects get serious, or if you notice any side-effects not
listed in this leaflet, please tell your doctor or pharmacist.
In this leaflet:
1) What Lorazepam Tablets are and what they are used for
2) Before you take Lorazepam Tablets
3) How to take Lorazepam Tablets
4) Possible side-effects
5) How to store Lorazepam Tablets
6) Further information


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buy Lorazepam online


1) What Lorazepam tablets are and what they are used for

The name of your medicine is Lorazepam (Ativan) Tablets. Lorazepam is a member of a group of medicines called benzodiazepines. It can help to relieve anxiety. Lorazepam is prescribed as short-term therapy for anxiety (2 -4 weeks), or sleeping difficulties due to anxiety. It may also be used as a sedative before surgery or operative dental treatment.
Lorazepam Tablets are not to be used for longer than 4 weeks, to treat mild or moderate anxiety in adults or for anxiety/insomnia in children.

2) Before you take Lorazepam tablets

Do not take Lorazepam Tablets:
• if you have severe breathing or chest problems
• if you are allergic to benzodiazepines or any of the other ingredients in Lorazepam Tablets (see list under ‘What Lorazepam Tablets contain’)
• if you have myasthenia gravis (very weak or tired muscles)
• if you have serious liver problems
• if you suffer from sleep apnoea (breathing problems when you are asleep)
• if you are breast-feeding, since the drug may pass into breast milk.
• if you are planning a pregnancy or are pregnant.

If you have been only prescribed Lorazepam Tablets for anxiety and no other medications, please consult with your doctor whether other medications should also be prescribed.


When special care is required with Lorazepam Tablets:

Please consult your doctor if any of the following apply:
• if you abuse or have in the past abused drugs or alcohol
• if you have a personality disorder. If so, you have a greater chance of becoming dependent on Lorazepam
• if you have any kidney or liver problems
• if you are suffering from depression, since Lorazepam may increase any suicidal feelings which you may have
• if you have suffered from depression before, since it could re-occur during treatment with Lorazepam
• if you suffer from breathing problems
• if you are suffering from an eye problem called glaucoma e.g. high pressure within the eye.

Taking other medicines

Tell your doctor or pharmacist that you are taking Lorazepam Tablets before taking any other medicine or if you enter hospital for treatment, or if you are taking any other medicines, including those which have not been prescribed by a doctor, since they may affect the way Lorazepam Tablets work.
Lorazepam Tablets may also affect the way other drugs work. In particular, you should tell your doctor if you are taking any other sedative (e.g.
barbiturates or antihistamines), anti-anxiety drugs, anti-depressants, strong pain killers (e.g. methadone), drugs for epilepsy (e.g. phenobarbital or
valproate), antihistamines, or drugs for mood or mental disorders (e.g. chlorpromazine, loxapine or clozapine), drugs for cataplexy; treating HIV; to
treat delusions or hallucinations; to help with indigestion (e.g. cisapride or omeprazole); muscle relaxants (e.g. baclofen and tizanidine); drugs for
addiction treatment (e.g. lofexidine and disulfram); TB drugs such as isazanid; antibiotics such as erthromycin; drugs to treat high blood
pressure; Parkinson’s disease drugs e.g. levodopa; oestrogen-containing contraceptives and drugs for asthma (theophylline). The dose of these drugs may need to be reduced before you can take Lorazepam Tablets. Lorazepam (Ativan)
Using Lorazepam Tablets with food or drink Grapefruit juice and drinks containing caffeine should be avoided as they can affect the way that Lorazepam Tablets work.

Pregnancy and breast-feeding

Do not take this medicine if you are pregnant, or might become pregnant, without consulting your doctor. Benzodiazepines, including lorazepam, may cause damage to the foetus if taken during early pregnancy.
If you take this medicine during late pregnancy or during labour, your baby, when born, may be less active than other babies, have a low body temperature, be floppy, or have breathing or feeding difficulties for a while.
Your baby’s response to the cold might be temporarily impaired. If this medicine is taken regularly in late pregnancy, your baby may develop withdrawal symptoms after birth.
Do not take this medicine if you are breast-feeding, since the drug may pass into breast milk, and cause the baby to be less active and unable to suckle.
Driving and using machines Lorazepam tablets may make you feel dizzy, sleepy or forgetful during the day, or may affect your concentration. This may affect your performance at skilled tasks such as driving machinery or operating machinery by affecting your vision or muscle function. You should not take part in any other
activities where this could put yourself or others at risk. You should avoid alcohol while you are taking Lorazepam, since this may make you very drowsy and seriously affect your ability to drive or use machines.

The medicine can affect your ability to drive as it may make you sleepy or dizzy

• Do not drive while taking this medicine until you know how it affects you.
• It is an offence to drive if this medicine affects your ability to drive.
• However, you would not be committing an offence if: However, you would not be committing an offence if:
• The medicine has been prescribed to treat a medical or dental problem and
• You have taken it according to the instructions given by the prescriber or in the information provided with the medicine and
• It was not affecting your ability to drive safely.
Talk to your doctor or pharmacist if you are not sure whether it is safe for you to drive while taking this medicine. Talk to your doctor or pharmacist if you are not sure whether it is safe for you to drive while taking this medicine.
Important information about some of the ingredients of Lorazepam.
Each tablet also contains the equivalent of 0.25mg of potassium. Too much potassium may be harmful if you are on a low potassium diet.
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

3) How to take Lorazepam tablets

Always take Lorazepam Tablets exactly as your doctor has told you. The label on your medicine should also tell you. You should check with your doctor or pharmacist if you are not sure. Lorazepam Tablets should be swallowed with water. Adults (and children over 13 years of age)

Anxiety: 1 to 4mg daily in divided doses. Your doctor will tell you how often to take your tablets.
– Sleeping Problems: 1 to 2mg before going to sleep. You should make sure that you will be able to sleep for 7 to 8 hours before taking your tablets.
– Before Surgery: 2 to 3mg the night before your operation and 2 to 4mg 1 or 2 hours before your operation.

Children (between 5 and 13 years of age)

• Before Surgery: The dose is usually between 0.5 and 2.5mg (depending on your child’s weight) at least 1 hour before your child’s operation.
• Lorazepam is not recommended for the treatment of anxiety or sleeping problems in children. Nor is it recommended for children below 5 years of

Elderly or patients with liver or kidney problems

– Older patients may be given lower doses. They may respond to half the usual adult dose or less.
Lorazepam is usually prescribed for short courses of treatment, lasting from a few days to 4 weeks including a dose reduction at the end. This reduces the risk of becoming dependent on Lorazepam Tablets, or suffering unpleasant effects when you stop taking them (See ‘If you stop taking Lorazepam Tablets’ section).
The beneficial effect of Lorazepam Tablets may be less apparent after several weeks of use. If you are given Lorazepam Tablets for more than 4 weeks, your doctor might want to take blood samples occasionally to check your blood and liver, since drugs like Lorazepam Tablets have occasionally affected blood and liver function.

If you take more Lorazepam Tablets than you should
If anyone has taken an overdose of Lorazepam Tablets (that is more than the doctor has prescribed), seek medical help immediately, either by calling your doctor, or going to the nearest casualty department. Always take the labelled medicine container with you, even if there are no tablets left.

If you forget to take Lorazepam Tablets

Do not take a double dose to make up for a forgotten tablet. If you forget to take a tablet for anxiety, you should take it as soon as you remember if it is less than 3 hours since your usual time. If more than 3 hours has passed from when you usually take your tablet, just take your next tablet when it is due.
If you forget to take a tablet for sleeping problems, only take it if you will be able to sleep for 7 to 8 hours afterwards.
If you stop taking Lorazepam Tablets
• After you have finished your prescribed treatment with Lorazepam, your
doctor will decide if you need further treatment.
• The number of Lorazepam Tablets and how often you take them should
always be reduced slowly before stopping them. This allows your body to
get used to being without your tablets, and reduces the risk of unpleasant
effects when you stop taking them. Your doctor will tell you how to do this.
• On stopping lorazepam, you may experience symptoms such as
headaches, muscle pain, anxiety, tension, depression, restlessness,
sweating, confusion or irritability. Your original sleeplessness may also
return. If you suffer from any of these symptoms, ask your doctor for
• Do not stop taking your tablets suddenly. This could lead to more serious symptoms such as loss of the sense of reality, feeling unreal or detached from life, and unable to feel emotion. Some patients have also
experienced numbness or tingling of the arms or legs, tinnitus (ringing sounds in the ears), oversensitivity to light, sound and touch, uncontrolled or overactive movements, twitching, shaking, feeling sick, being sick, stomach upsets or stomach pain, loss of appetite, agitation, abnormally fast heartbeats, panic attacks, dizziness or feeling that you are about to fall, memory loss, hallucinations, feeling stiff and unable to move easily, feeling very warm, convulsions (sudden uncontrolled shaking or jerking of the body).
• Patients taking anti-depressants and patients with seizure disorders may be more likely to experience convulsions.
If you suffer from any of these symptoms, ask your doctor for advice immediately.

4) Possible side-effects
Like all medicines, Lorazepam Tablets can cause side-effects, although not everybody gets them. These are usually not serious and do not last long.
If you experience any of the following more rare unwanted effects, you should tell your doctor immediately (these effects are more likely to occur in children and elderly patients): Restlessness, agitation, irritability, aggressiveness, violent anger, sleeping difficulties, nightmares, hallucinations, personality changes, sexual arousal, abnormal behaviour or false beliefs.

Unexplained bleeding and/or bruising; increased risk of infections e.g. frequent sore throats, mouth ulcers, weakness and pale skin as these are symptoms of blood dyscrasia.
Severe allergic reactions e.g. difficulty in breathing, swelling of the lips, mouth, tongue, throat, hands, feet and /or severe faintness or dizziness. Jaundice e.g. yellowing of the skin, eyes, nose, mouth, pale coloured stools
(faeces) and dark coloured urine.
However, you should tell your doctor if any of the following symptoms are severe or become troublesome:
Daytime drowsiness, dizziness, reduced alertness, poor muscle control, muscle weakness, fatigue, hypersensitivity including anaphylaxis (allergic reactions), confusion, depression, numbed emotions, difficulty controlling urges and impulses to speak, act or show emotions, a feeling of well-being for no reason, appetite changes, sleep problems, changes in sex drive, decreased orgasm, thoughts of harming or killing yourself, becoming dependent on Lorazepam, headache, slurred speech, memory loss or forgetfulness, trembling or shaking, impaired consciousness (ultimately coma), problems with vision including double vision or blurred vision, worsening of sleep apnoea e.g. loud snoring, restlessness and choking/gasping during the night, breathing difficulties, stomach upsets, nausea, constipation, changes in the amount of saliva in the mouth, skin problems such as rashes and inflammation, erectile dysfunction. Other rare unwanted effects, which you may not be aware of whilst taking. Lorazepam (Ativan)

Lorazepam, include blood or liver function changes, or low blood pressure, or low body temperature.
If any of the side-effects get serious, or if you notice any side-effects not
listed in this leaflet, please tell your doctor or pharmacist.
Reporting side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.

5) How to store Lorazepam tablets

• Keep out of the sight and reach of children.
• Do not take Lorazepam Tablets after the expiry date which is stated on the carton after EXP.
• The expiry date refers to the last day of the month.
• Do not store above 25°C. Store in the original package.
• Return any unused tablets to your pharmacist. Only keep them if your doctor tells you to.
• If the tablets become discoloured or show any other signs of deterioration, you should seek the advice of your pharmacist who will tell you what to
• Medicines should not be disposed of via wastewater or household waste.
Ask your pharmacist how to dispose of medicines no longer required.
These measures will help protect the environment.

6) Further information

What Lorazepam Tablets contain
Each tablet contains 2.5mg of Lorazepam.
The other ingredients are lactose monohydrate, cellulose microcrystalline,
polacrilin potassium, quinoline yellow aluminium lake E104, magnesium
stearate and lactose anhydrous.
What Lorazepam Tablets look like and the contents of the pack
Lorazepam Tablets are yellow capsule-shaped tablets, with ‘L Z’ on one
face and with a break bar on the other face.
Lorazepam Tablets are available in blister packs of 30 tablets.
PL 10383/1787 Temesta 2.5mg Tablets/Lorazepam 2.5mg Tablets POM
Who makes and repackages your medicine?
Your medicine is manufactured by Sanofi Winthrop Industrie, Compiegne,
France. Procured from within the EU and repackaged by the Product
Licence Holder: Primecrown Ltd., 4/5 Northolt Trading Estate, Northolt,
Middlesex, UB5 5QS.
Leaflet date: 08.08.2016
Temesta is a register trademark of Wyeth LLC, USA.


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